Association between RFC1 A80G polymorphism and the susceptibility to nonsyndromic cleft lip with or without cleft palate: a meta-analysis

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Association between Maternal MTHFR Polymorphisms and Nonsyndromic Cleft Lip with or without Cleft Palate in Offspring, A Meta-Analysis Based on 15 Case-Control Studies

Background The methylenetetrahydrofolate reductase (MTHFR) is thought to be involved in the development of nonsyndromic cleft lip with or without cleft palate (NSCL/P). However, conflicting results have been obtained when evaluating the association between maternal MTHFR C677T and A1298C polymorphisms and the risk of NSCL/P. In light of this gap, a meta-analysis of all eligible case-control stu...

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Association between IRF6 and 8q24 polymorphisms and nonsyndromic cleft lip with or without cleft palate: Systematic review and meta‐analysis

BACKGROUND We conducted a systematic review and meta-analysis of interferon regulatory factor 6 and 8q24 polymorphisms with nonsyndromic cleft lip with/without cleft palate (NSCL/P). METHODS Data extraction was independently performed by two reviewers. Genotypic effects of four polymorphisms from 31 studies were pooled separately by ethnicity using a mixed-effect logit model with accounting f...

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BMP4 rs17563 polymorphism and nonsyndromic cleft lip with or without cleft palate

BACKGROUND Previous studies have investigated the relationship between human bone morphogenetic protein 4 gene (BMP4) rs17563 polymorphism and nonsyndromic cleft lip with or without cleft palate (NSCL/P). However, the results remained inconsistent. Therefore, we conducted a meta-analysis to assess the effect of BMP4 rs17563 polymorphism on NSCL/P. METHODS Electronic searches in 5 databases we...

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association between maternal mthfr polymorphisms and nonsyndromic cleft lip with or without cleft palate in offspring, a meta-analysis based on 15 case-control studies

background: the methylenetetrahydrofolate reductase (mthfr) is thought to be involved in the development of nonsyndromic cleft lip with or without cleft palate (nscl/p). however, conflicting results have been obtained when evaluating the association between maternal mthfr c677t and a1298c polymorphisms and the risk of nscl/p. in light of this gap, a meta-analysis of all eligible case-control st...

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FOXE1 association with both isolated cleft lip with or without cleft palate, and isolated cleft palate.

Nonsyndromic orofacial clefts are a common complex birth defect caused by genetic and environmental factors and/or their interactions. A previous genome-wide linkage scan discovered a novel locus for cleft lip with or without cleft palate (CL/P) at 9q22-q33. To identify the etiologic gene, we undertook an iterative and complementary fine mapping strategy using family-based CL/P samples from Col...

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ژورنال

عنوان ژورنال: Annals of Translational Medicine

سال: 2019

ISSN: 2305-5839,2305-5847

DOI: 10.21037/atm.2019.12.30